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Recent Publications

An automated microdroplet passive pumping platform for high-speed and packeted microfluidic flow applications (Sat, 23 Jan 2010 21:46:14 +0000)

PDF Resto PJ, Mogen BJ, Berthier E, Williams JC Abstract: Surface tension driven passive pumping is a microfluidic technology that uses the surface tension present in small droplets to generate flow. To enhance the potential of this type of passive pumping, a new ‘micro passive pumping’ technique has been developed that allows for high throughput fluidic delivery [...]

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Massively parallel signal processing using the graphics processing unit for real-time brain–computer interface feature extraction (Tue, 29 Sep 2009 05:43:46 +0000)

PDF Wilson JA, Williams JC Abstract: The clock speeds of modern computer processors have nearly plateaued in the past 5 years. Consequently, neural prosthetic systems that rely on processing large quantities of data in a short period of time face a bottleneck, in that it may not be possible to process all of the data recorded from [...]

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Positioning and guidance of neurons on gold surfaces by directed assembly of proteins using Atomic Force Microscopy (Sat, 18 Apr 2009 00:33:13 +0000)

PDF Staii C, Viesselmann C, Ballweg J, Shi L, Liu GY, Williams JC, Dent EW, Coppersmith SN, Eriksson MA. Abstract: We demonstrate that Atomic Force Microscopy nanolithography can be used to control effectively the adhesion, growth and interconnectivity of cortical neurons on Au surfaces. We demonstrate immobilization of neurons at well-defined locations on Au surfaces using two [...]

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Research Projects


Neural Prosthetics

We study several aspects of human neural prosthetics, including hardware and instrumentation, the development of new software and algorithms, human factors engineering, and creating new interface methods.

People: Adam Wilson, Leo Walton


in vivo Device Development

The goal of this project to develop and characterize implanted chronic neural recording devices. These electrodes with incorporated drug delivery should be capable of recording consistent neural activity for years with minimal risk of complications.

People: Jiwan Kim, Joe Hippensteel, Adam Wilson


in vitro Device Development

The goal of this project is to develop "Lab-on-a-chip" microfluidic systems that allow the micro-environment of a cell culture or brain slice to be finely regulated. Unlike the standard macro-scale systems used for decades, microfluidics allows the researcher to expose multiple regions of a slice or culture to multiple environments simultaneously, allowing for control several orders of magnitude better than had previously been possible.

People: Alex Blake, Yu Huang, Steve Skroch, Pedro J. Resto